COVID-19 epidemic in the Brazilian state of Amazonas was driven by long-term persistence of endemic SARS-CoV-2 lineages and the recent emergence of the new Variant of Concern P.1

Doi: 10.21203/

Prado T, Fumian TM, Mannarino CF, Resende PC, Motta FC, Eppinghaus ALF, et al. Wastewater-based epidemiology as a useful tool to track SARS-CoV-2 and support public health policies at municipal level in Brazil. Water Res. 2021;191:116810. Available from:

Nascimento VA Do, Corado A de LG, Nascimento FO Do, da Costa ÁKA, Duarte DCG, Luz SLB, et al. Genomic and phylogenetic characterisation of an imported case of sars-cov-2 in Amazonas state, brazil. Mem Inst Oswaldo Cruz. 2020;115(8):1–6. Available from:

Resende PC, Delatorre E, Gräf T, Mir D, Motta FC, Appolinario LR, et al. Evolutionary dynamics and dissemination pattern of the SARS-CoV-2 lineage B.1.1.33 during the early pandemic phase in Brazil. Front Microbiol. 2020. Available from:

Henrique Santos Paiva M, Ribeiro Duarte Guedes D, Docena C, Filgueira Bezerra M, Zimmer Dezordi F, Ceschini Machado L, et al. Multiple introductions followed by ongoing community spread of SARS-CoV-2 at one of the largest metropolitan areas in the Northeast of Brazil. Viruses. 2020;12(12):1414. Available from:

Delatorre E, Mir D, Graf T, Bello G. Tracking the onset date of the community spread of SARS-CoV-2 in Western Countries. Mem Inst Oswaldo Cruz. 2020;1–13. Available from:

Mir D, Rego N, Resende PC, Lopez-Tort F, Fernandez-Calero T, Noya V, et al. Recurrent dissemination of SARS-CoV-2 through the Uruguayan-Brazilian border. medRxiv. 2021;1–27. Available from:

Nonaka CK V., Franco MM, Gräf T, Mendes AVA, Aguiar RS, Giovanetti M, et al. Genomic Evidence of a Sars-Cov-2 Reinfection Case With E484K Spike Mutation in Brazil. Preprints. 2021;1–6. Available from:

Resende PC, Delatorre E, Gräf T, Mir D, Motta F do C, Appolinario LR, et al. Genomic surveillance of SARS-CoV-2 reveals community transmission of a major lineage during the early pandemic phase in Brazil. bioRxiv. 2020;1–28. Available from:

Resende PC, Motta FC, Roy S, Appolinario L, Fabri A, Xavier J, et al. SARS-CoV-2 genomes recovered by long amplicon tiling multiplex approach using nanopore sequencing and applicable to other sequencing platforms. bioRxiv. 2020;1–11. Available from: